Photodynamic therapy

PDT for DFU

Diabetic foot ulcers (DFU) are an underestimated and neglected aspect of a disease that is growing in prevalence on a global scale. 

The 5 year mortality for DFU is comparable to the 5 year mortality across all cancers. Amputation of a DFU costs tens of thousands of pounds (GBP) per year. Treatment of a DFU using the current techniques for a year costs just under 11,000 GBP.  In total, it is estimated that DFUs cost the NHS 1.8 million pounds per year. 

In our lab we aim to put an end to this by using photodynamic therapy (PDT) to treat the wound in a rapid, cost-effective and pain-free manner using novel technology and innovative techniques.

OLED-mediated PDT

Organic light emitting diodes (OLEDs) are a light source which utilise organic semiconductors. OLEDs boast a higher efficiency than conventional lamps used for medical treatment and provide uniform and even light distribution compared to the pin-point nature of lasers or focused areas of LED arrays.

PDT for the future

With alternatives to antibiotic therapy becoming more apparent in modern healthcare, treatments such as Photodynamic therapy are seeing new and increasing usage. However, the large form factor of the equipment needed is seen as a large barrier for treating patients. This is especially important for patients within rural or isolated communities or patients who may struggle to attend hospital clinics.

Part of our lab's aims are to close the healthcare gap, bringing state-of-the-art healthcare to all communities through patient-focussed research and innovation.